The kit adopts magnetic beads with unique separation function and a unique buffer system to separate and purify high-quality genomic DNA from blood spots. The unique embedded magnetic beads have strong affinity for nucleic acid under certain conditions, and when the conditions change, the magnetic beads will release adsorbed nucleic acid, thus achieving the purpose of fast separation and purification of nucleic acid. The product is perfectly matched with TGuide S32 Automated Nucleic Acid Extractor. Magnetic beads are adsorbed, transferred and released by special magnetic rods, thus realizing the transfer of magnetic beads and nucleic acids. The whole experimental process is safe and convenient. The extracted genomic DNA fragments are large in size, with high purity and stable and reliable quality. The DNA purified by the kit is suitable for various conventional operations, including enzyme digestion, PCR, library construction, Southern blot and other experiments.